Other emerging hair growth drugs on hair loss
Although Rogaine and Propecia are the only two drugs currently approved by the Food and Drug Administration to combat hereditary balding there are several other drugs which have shown great promise in restoring hair loss. These are not likely to be miracle cures, but they may be more effective than current versions of Rogaine and Propecia, and may display traits more suited to your needs.
You should know what other drugs may soon be available besides Rogaine and Propecia. All of these drugs are still being tested. Some of them are being seriously investigated by large pharmaceutical companies which are investing millions of dollars to make them work.
The main group of drugs being investigated for treatment of hereditary hair loss are called antiandrogens. First the promising antiandrogen drugs will be reviewed followed by a brief mention of some of the other promising drugs that are still in early stages of testing:
Dutasteride
Dutasteride is another 5 alpha reductase inhibitor. It blocks, receptors 1 and 2, Finesteride also blocks receptor 2. The effect of Dutasteride is to decrease OHT. It has been approved in the U.S for Benign Prostatic Hypertrophy in November 2002. It is still undergoing phase II and phase III trials for hair loss. The results do look promising. Similar to Finestride, it will have some side effects on male sexual function.
Antiandrogens
Antiandrogens are drugs that prevent androgens, or what are also called male hormones, from working. These are a group of drugs that have shown the most promise in being able to provide a cure for hereditary hair loss.
Antiandrogens are used to treat many different ailments and one of the side effects noticed of these usages has been the promotion of hair growth all over the body. These kinds of drugs are believed to be effective in fighting hereditary hair loss because most experts believe that this type of hair loss is related to the activity of male hormones in people with the wrong genes. As noted above, tests on the balding scalps of people with hereditary hair loss show unusual amounts of a male hormone called dehydrotestosterone (DHT) present, which has been identified as a main culprit in causing hereditary hair loss.
What are the side effects of antiandrogens?
While antiandrogens are effective in fighting hair loss they also have many severe side effects, which are especially harmful for men because as should be obvious men need male hormones to work much more than women do. Antiandrogens generally cause men to lose male physical characteristics and sexual desire and potency. are antiandrogens safer for women?
Antiandrogens are generally safer for women. Since women are less damaged by the side effects of antiandrogens they are more effectively treated by them. In Europe, antiandrogens have been officially used to treat hereditary hair loss in women for years. Cyproterone acetate is one strong antiandrogen that has been effectively used to treat women with hereditary hair loss in Europe and in other parts of the world.
Is there any hope for developing antiandrogen treatment for men?
Yes! Researchers have been trying to develop antiandrogen treatments that are safe for men with hereditary hair loss. The trick for researchers has been to try to find a way of using antiandrogens that promote hair loss on the head without causing the other side effects associated with them. Some antiandrogens have been developed which have gone some way in doing this. Finasteride, the active drug in Propecia is in fact an example of one such antiandrogen, but it is not considered a normal antiandrogen because it does not directly counteract androgens but only indirectly does so with one specific type. Other antiandrogens that are being tested for fighting hair loss in men include Cimetidine, Spironoclactone, and Progesterone.
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